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Influenza Phylogeny (Nextstrain)

Phylogeny of seasonal influenza — H3N2, H1N1pdm and type B. Evolution of haemagglutinin and predictions for vaccine strain selection.

Public source Zdroj: Nextstrain Influenza · GISAID EpiFlu Aktualizace: Weekly (Nextstrain server) influenzagenomicsphylogenyNextstrain

Nextstrain maintains continuously updated phylogenetic trees for seasonal influenza — a key tool for tracking antigenic drift and selecting strains for vaccines.

Available Nextstrain influenza builds

SubtypeSegmentWindowLink
H3N2HA (haemagglutinin)2 yearsnextstrain.org/flu/seasonal/h3n2/ha/2y
H3N2NA (neuraminidase)2 yearsnextstrain.org/flu/seasonal/h3n2/na/2y
H1N1pdmHA2 yearsnextstrain.org/flu/seasonal/h1n1pdm/ha/2y
Type B/VicHA2 yearsnextstrain.org/flu/seasonal/vic/ha/2y

What the tree shows

  • Antigenic clades — colour-coded groups sharing a similar antigen
  • Vaccine strains — the WHO-recommended strains for the season are marked
  • Geographic distribution — where each sequence comes from
  • HA mutations — amino-acid substitutions mapped onto the tree
Open Nextstrain — H3N2 HA (2 years)

Nextstrain Influenza · Bedford Lab · sequences from GISAID EpiFlu